What Is The Risk Of Chromosomal Abnormalities

Currently fetal chromosomal abnormalities due to maternal age have been reported to include trisomy 21 trisomy 18 trisomy 13 triple X syndrome and Klinefelters syndrome 5. This is because errors in meiosis may be more likely to happen as a result of the aging process.

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A woman age 35 years or older is at higher risk of having a baby with a chromosomal abnormality.

What is the risk of chromosomal abnormalities. Therefore pregnancy in advanced age is a critical risk factor for fetal chromosomal abnormalities 2-4. The eggs begin to mature during puberty. Risk factors include folate deficiency drinking alcohol or smoking during pregnancy poorly controlled diabetes and a mother over the age of 35 years old.

Women are born with all of their eggs already in their ovaries. Birth defects may result from genetic or chromosomal disorders exposure to certain medications or chemicals or certain infections during pregnancy. However errors in cell division called nondisjunction can result in cells with too few or too many copies of a whole chromosome or a piece of a chromosome16 Some factors such as when a mother is of advanced maternal age older then 35 years can increase the risk for chromosome abnormalities in a pregnancy1.

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